Nierenkrebs

[Koli]

Was ist ein Onkozytom in der Niere?

[Tiger 2002]

RE: Nierenkrebs


Guten Tag,

Ein Onkozytom ist ein seltener GUTARTIGER Nierentumor.
Dieser Tumor macht etwa 4% aller Nirentumore aus und hat ein gute Prognose.

[Prof. Wust]

RE: Nierenkrebs


Es ist nicht hundertprozentig sicher, dass ein Onkozytom der Niere immer gutartig ist. Es stimmt aber wohl im allgemeinen. Hat häufig einen familiären Hintergrund.
Wenn Sie es genauer wissen wollen, lesen Sie Amin et al. 1998:

Familial renal oncocytoma: clinicopathological study of 5 families.
AU: Weirich,-G; Glenn,-G; Junker,-K; Merino,-M; Storkel,-S; Lubensky,-I; Choyke,-P; Pack,-S; Amin,-M; Walther,-M-M; Linehan,-W-M; Zbar,-B
AB: PURPOSE: We analyzed familial renal oncocytoma to provide a foundation for studies aimed at defining genes involved in the pathogenesis of renal oncocytoma. MATERIALS AND METHODS: We describe 5 families with multiple members affected with renal oncocytoma. Tumors were analyzed pathologically, and affected and nonaffected members were screened clinically and genetically. RESULTS: We identified 12 affected male and 3 affected female (ratio 4:1) individuals in the 5 families. In affected family members renal oncocytomas were often multiple and bilateral. No metastatic disease was observed. Most renal oncocytomas were detected incidentally in asymptomatic individuals or during screening of asymptomatic members of renal oncocytoma families. One identical twin pair was affected with bilateral multiple renal oncocytomas. CONCLUSIONS: Renal oncocytoma may be inherited in some families.